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Differential regulation of MMPs by E2F1, Sp1 and NF-kappa B controls the small cell lung cancer invasive phenotype

BACKGROUND: E2F1 transcription factor plays a vital role in the regulation of diverse cellular processes including cell proliferation, apoptosis, invasion and metastasis. E2F1 overexpression has been demonstrated in small cell lung cancer (SCLC), and extensive metastasis in early phase is the most i...

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Detalles Bibliográficos
Autores principales: Li, Zunling, Guo, Yanxia, Jiang, Hanming, Zhang, Tingguo, Jin, Changzhu, Young, Charles YF, Yuan, Huiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077048/
https://www.ncbi.nlm.nih.gov/pubmed/24755270
http://dx.doi.org/10.1186/1471-2407-14-276