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High efficiency of alphaviral gene transfer in combination with 5-fluorouracil in a mouse mammary tumor model

BACKGROUND: The combination of virotherapy and chemotherapy may enable efficient tumor regression that would be unachievable using either therapy alone. In this study, we investigated the efficiency of transgene delivery and the cytotoxic effects of alphaviral vector in combination with 5-fluorourac...

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Detalles Bibliográficos
Autores principales: Zajakina, Anna, Vasilevska, Jelena, Zhulenkovs, Dmitry, Skrastina, Dace, Spaks, Artjoms, Plotniece, Aiva, Kozlovska, Tatjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077127/
https://www.ncbi.nlm.nih.gov/pubmed/24950740
http://dx.doi.org/10.1186/1471-2407-14-460