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High efficiency of alphaviral gene transfer in combination with 5-fluorouracil in a mouse mammary tumor model
BACKGROUND: The combination of virotherapy and chemotherapy may enable efficient tumor regression that would be unachievable using either therapy alone. In this study, we investigated the efficiency of transgene delivery and the cytotoxic effects of alphaviral vector in combination with 5-fluorourac...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077127/ https://www.ncbi.nlm.nih.gov/pubmed/24950740 http://dx.doi.org/10.1186/1471-2407-14-460 |