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Primary-tertiary diamine-catalyzed Michael addition of ketones to isatylidenemalononitrile derivatives
Simple primary-tertiary diamines easily derived from natural primary amino acids were used to catalyze the Michael addition of ketones with isatylidenemalononitrile derivatives. Diamine 1a in combination with D-CSA as an additive provided Michael adducts in high yield (up to 94%) and excellent enant...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077384/ https://www.ncbi.nlm.nih.gov/pubmed/24991242 http://dx.doi.org/10.3762/bjoc.10.91 |