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A tandem Mannich addition–palladium catalyzed ring-closing route toward 4-substituted-3(2H)-furanones

A facile route towards highly functionalized 3(2H)-furanones via a sequential Mannich addition–palladium catalyzed ring closing has been elaborated. The reaction of 4-chloroacetoacetate esters with imines derived from aliphatic and aromatic aldehydes under palladium catalysis afforded 4-substituted...

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Detalles Bibliográficos
Autores principales: John, Jubi, Târcoveanu, Eliza, Jones, Peter G, Hopf, Henning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077403/
https://www.ncbi.nlm.nih.gov/pubmed/24991301
http://dx.doi.org/10.3762/bjoc.10.150