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A tandem Mannich addition–palladium catalyzed ring-closing route toward 4-substituted-3(2H)-furanones
A facile route towards highly functionalized 3(2H)-furanones via a sequential Mannich addition–palladium catalyzed ring closing has been elaborated. The reaction of 4-chloroacetoacetate esters with imines derived from aliphatic and aromatic aldehydes under palladium catalysis afforded 4-substituted...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077403/ https://www.ncbi.nlm.nih.gov/pubmed/24991301 http://dx.doi.org/10.3762/bjoc.10.150 |