Regioselective S(N)2' Mitsunobu reaction of Morita–Baylis–Hillman alcohols: A facile and stereoselective synthesis of α-alkylidene-β-hydrazino acid derivatives

A highly regioselective S(N)2' Mitsunobu reaction between Morita–Baylis–Hillman (MBH) alcohols, azodicarboxylates, and triphenylphosphine is developed, which provides an easy access to α-alkylidene-β-hydrazino acid derivatives in high yields and good stereoselectivity. This reaction represents...

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Detalles Bibliográficos
Autores principales: Xu, Silong, Shang, Jian, Zhang, Junjie, Tang, Yuhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077529/
https://www.ncbi.nlm.nih.gov/pubmed/24991249
http://dx.doi.org/10.3762/bjoc.10.98

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077529/
https://www.ncbi.nlm.nih.gov/pubmed/24991249
http://dx.doi.org/10.3762/bjoc.10.98

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