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Calcineurin Mediates Synaptic Scaling Via Synaptic Trafficking of Ca(2+)-Permeable AMPA Receptors

Homeostatic synaptic plasticity is a negative-feedback mechanism for compensating excessive excitation or inhibition of neuronal activity. When neuronal activity is chronically suppressed, neurons increase synaptic strength across all affected synapses via synaptic scaling. One mechanism for this ch...

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Detalles Bibliográficos
Autores principales: Kim, Seonil, Ziff, Edward B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077568/
https://www.ncbi.nlm.nih.gov/pubmed/24983627
http://dx.doi.org/10.1371/journal.pbio.1001900