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L-Carnitine Prevents Progression of Non-Alcoholic Steatohepatitis in a Mouse Model with Upregulation of Mitochondrial Pathway

Non-alcoholic steatohepatitis (NASH) is a severe form of non-alcoholic fatty liver disease characterized by lobular inflammation, hepatocellular ballooning, and fibrosis with an inherent risk for progression to cirrhosis and hepatocellular carcinoma (HCC). Mitochondrial dysfunction appears to play a...

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Detalles Bibliográficos
Autores principales: Ishikawa, Hisashi, Takaki, Akinobu, Tsuzaki, Ryuichiro, Yasunaka, Tetsuya, Koike, Kazuko, Shimomura, Yasuyuki, Seki, Hiroyuki, Matsushita, Hiroshi, Miyake, Yasuhiro, Ikeda, Fusao, Shiraha, Hidenori, Nouso, Kazuhiro, Yamamoto, Kazuhide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077577/
https://www.ncbi.nlm.nih.gov/pubmed/24983359
http://dx.doi.org/10.1371/journal.pone.0100627