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L-Carnitine Prevents Progression of Non-Alcoholic Steatohepatitis in a Mouse Model with Upregulation of Mitochondrial Pathway
Non-alcoholic steatohepatitis (NASH) is a severe form of non-alcoholic fatty liver disease characterized by lobular inflammation, hepatocellular ballooning, and fibrosis with an inherent risk for progression to cirrhosis and hepatocellular carcinoma (HCC). Mitochondrial dysfunction appears to play a...
Autores principales: | Ishikawa, Hisashi, Takaki, Akinobu, Tsuzaki, Ryuichiro, Yasunaka, Tetsuya, Koike, Kazuko, Shimomura, Yasuyuki, Seki, Hiroyuki, Matsushita, Hiroshi, Miyake, Yasuhiro, Ikeda, Fusao, Shiraha, Hidenori, Nouso, Kazuhiro, Yamamoto, Kazuhide |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077577/ https://www.ncbi.nlm.nih.gov/pubmed/24983359 http://dx.doi.org/10.1371/journal.pone.0100627 |
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