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Engineered single nucleotide polymorphisms in the mosquito MEK docking site alter Plasmodium berghei development in Anopheles gambiae

BACKGROUND: Susceptibility to Plasmodium infection in Anopheles gambiae has been proposed to result from naturally occurring polymorphisms that alter the strength of endogenous innate defenses. Despite the fact that some of these mutations are known to introduce non-synonymous substitutions in codin...

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Detalles Bibliográficos
Autores principales: Brenton, Ashley A, Souvannaseng, Lattha, Cheung, Kong, Anishchenko, Michael, Brault, Aaron C, Luckhart, Shirley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077580/
https://www.ncbi.nlm.nih.gov/pubmed/24957684
http://dx.doi.org/10.1186/1756-3305-7-287