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Effects of BMI, Fat Mass, and Lean Mass on Asthma in Childhood: A Mendelian Randomization Study

BACKGROUND: Observational studies have reported associations between body mass index (BMI) and asthma, but confounding and reverse causality remain plausible explanations. We aim to investigate evidence for a causal effect of BMI on asthma using a Mendelian randomization approach. METHODS AND FINDIN...

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Detalles Bibliográficos
Autores principales: Granell, Raquel, Henderson, A. John, Evans, David M., Smith, George Davey, Ness, Andrew R., Lewis, Sarah, Palmer, Tom M., Sterne, Jonathan A. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077660/
https://www.ncbi.nlm.nih.gov/pubmed/24983943
http://dx.doi.org/10.1371/journal.pmed.1001669