GSK3A Is Redundant with GSK3B in Modulating Drug Resistance and Chemotherapy-Induced Necroptosis

Glycogen Synthase Kinase-3 alpha (GSK3A) and beta (GSK3B) isoforms are encoded by distinct genes, are 98% identical within their kinase domain and perform similar functions in several settings; however, they are not completely redundant and, depending on the cell type and differentiative status, the...

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Detalles Bibliográficos
Autores principales: Grassilli, Emanuela, Ianzano, Leonarda, Bonomo, Sara, Missaglia, Carola, Cerrito, Maria Grazia, Giovannoni, Roberto, Masiero, Laura, Lavitrano, Marialuisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077702/
https://www.ncbi.nlm.nih.gov/pubmed/24984063
http://dx.doi.org/10.1371/journal.pone.0100947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077702/
https://www.ncbi.nlm.nih.gov/pubmed/24984063
http://dx.doi.org/10.1371/journal.pone.0100947

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