Regulation of the JNK3 Signaling Pathway during Islet Isolation: JNK3 and c-fos as New Markers of Islet Quality for Transplantation

Stress conditions generated throughout pancreatic islet processing initiate the activation of pro-inflammatory pathways and beta-cell destruction. Our goal is to identify relevant and preferably beta-specific markers to assess the activation of beta-cell stress and apoptotic mechanisms, and therefor...

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Detalles Bibliográficos
Autores principales: Abdelli, Saida, Papas, Klearchos K., Mueller, Kate R., Murtaugh, Mike P., Hering, Bernhard J., Bonny, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077704/
https://www.ncbi.nlm.nih.gov/pubmed/24983249
http://dx.doi.org/10.1371/journal.pone.0099796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077704/
https://www.ncbi.nlm.nih.gov/pubmed/24983249
http://dx.doi.org/10.1371/journal.pone.0099796

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