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Regulation of the JNK3 Signaling Pathway during Islet Isolation: JNK3 and c-fos as New Markers of Islet Quality for Transplantation
Stress conditions generated throughout pancreatic islet processing initiate the activation of pro-inflammatory pathways and beta-cell destruction. Our goal is to identify relevant and preferably beta-specific markers to assess the activation of beta-cell stress and apoptotic mechanisms, and therefor...
Autores principales: | Abdelli, Saida, Papas, Klearchos K., Mueller, Kate R., Murtaugh, Mike P., Hering, Bernhard J., Bonny, Christophe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077704/ https://www.ncbi.nlm.nih.gov/pubmed/24983249 http://dx.doi.org/10.1371/journal.pone.0099796 |
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