L-Ascorbate Attenuates the Endotoxin-Induced Production of Inflammatory Mediators by Inhibiting MAPK Activation and NF-κB Translocation in Cortical Neurons/Glia Cocultures

In response to acute insults to the central nervous system, such as pathogen invasion or neuronal injuries, glial cells become activated and secrete inflammatory mediators such as nitric oxide (NO), cytokines, and chemokines. This neuroinflammation plays a crucial role in the pathophysiology of chro...

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Detalles Bibliográficos
Autores principales: Huang, Ya-Ni, Lai, Chien-Cheng, Chiu, Chien-Tsai, Lin, Jhen-Jhe, Wang, Jia-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077707/
https://www.ncbi.nlm.nih.gov/pubmed/24983461
http://dx.doi.org/10.1371/journal.pone.0097276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077707/
https://www.ncbi.nlm.nih.gov/pubmed/24983461
http://dx.doi.org/10.1371/journal.pone.0097276

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