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Glycolipid Binding Preferences of Shiga Toxin Variants
The major virulence factor of Shiga toxin producing E. coli, is Shiga toxin (Stx), an AB(5) toxin that consists of a ribosomal RNA-cleaving A-subunit surrounded by a pentamer of receptor-binding B subunits. The two major isoforms, Stx1 and Stx2, and Stx2 variants (Stx2a-h) significantly differ in to...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077739/ https://www.ncbi.nlm.nih.gov/pubmed/24983355 http://dx.doi.org/10.1371/journal.pone.0101173 |