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Trim28 Contributes to EMT via Regulation of E-Cadherin and N-Cadherin in Lung Cancer Cell Lines

In previous work, we demonstrated that transcription factor Trim28 (Tripartite motif containing 28) plays a tumor-suppressor role in early-staged adenocarcinoma of the lung due to its ability to restrain transcription of cell cycle-regulating genes. Herein we examine Trim28's role in the epithe...

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Detalles Bibliográficos
Autores principales: Chen, Lu, Muñoz-Antonia, Teresita, Cress, W. Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077753/
https://www.ncbi.nlm.nih.gov/pubmed/24983967
http://dx.doi.org/10.1371/journal.pone.0101040