IL-33 targeting attenuates intestinal mucositis and enhances effective tumour chemotherapy in mice

Intestinal damage and severe diarrhea are serious side effects of cancer chemotherapy and constrain the usage of most such therapies. Here we show that IL-33 mediates the severe intestinal mucositis in mice treated with Irinotecan (CPT-11), a commonly used cancer chemotherapeutic agent. Systemic CPT...

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Detalles Bibliográficos
Autores principales: Guabiraba, R, Besnard, A G, Menezes, G B, Secher, T, Jabir, M S, Amaral, S S, Braun, H, Lima-Junior, R C P, Ribeiro, R A, Cunha, F Q, Graham, G J, Teixeira, M M, Beyaert, R, Liew, F Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077764/
https://www.ncbi.nlm.nih.gov/pubmed/24424522
http://dx.doi.org/10.1038/mi.2013.124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077764/
https://www.ncbi.nlm.nih.gov/pubmed/24424522
http://dx.doi.org/10.1038/mi.2013.124

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