Cargando…

The Role of Hypoxia Inducible Factor-1 Alpha in Bypassing Oncogene-Induced Senescence

Oncogene induced senescence (OIS) is a sustained anti-proliferative response acutely induced in primary cells via activation of mitogenic oncogenes such as Ras/BRAF. This mechanism acts as an initial barrier preventing normal cells transformation into malignant cell. Besides oncogenic activation and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kilic Eren, Mehtap, Tabor, Vedrana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077769/ https://www.ncbi.nlm.nih.gov/pubmed/24984035 http://dx.doi.org/10.1371/journal.pone.0101064

Ejemplares similares

Targeting PI3K/Akt represses Hypoxia inducible factor-1α activation and sensitizes Rhabdomyosarcoma and Ewing’s sarcoma cells for apoptosis
por: Kilic-Eren, Mehtap, et al.
Publicado: (2013)

Correction: The Role of Hypoxia Inducible Factor-1 Alpha in Bypassing Oncogene-Induced Senescence
Publicado: (2014)

Resveratrol Induced Premature Senescence Is Associated with DNA Damage Mediated SIRT1 and SIRT2 Down-Regulation
por: Kilic Eren, Mehtap, et al.
Publicado: (2015)

Oncogenic WIP1 phosphatase attenuates the DNA damage response and sensitizes p53 mutant Jurkat cells to apoptosis
por: Eren, Mehtap Kilic, et al.
Publicado: (2021)

The role of hypoxia-inducible factor-1 alpha in TEMPI syndrome
por: Khan, Sujoy
Publicado: (2011)

The Role of Hypoxia-Inducible Factor-1 Alpha in Renal Disease
por: Liu, Huixia, et al.
Publicado: (2022)

Macroautophagy and the Oncogene-Induced Senescence
por: Grasso, Daniel, et al.
Publicado: (2014)

Induction and transmission of oncogene-induced senescence
por: Rattanavirotkul, Nattaphong, et al.
Publicado: (2020)

Caspase-2 regulates oncogene-induced senescence
por: Gitenay, Delphine, et al.
Publicado: (2014)

The role of hypoxia-inducible factor-1 alpha in multidrug-resistant breast cancer
por: Yong, Liyun, et al.
Publicado: (2022)

The Study of Expression of Hypoxia-Inducible Factor-1 Alpha (HIF-1 Alpha) and Hypoxia-Inducible Factor-2 Alpha (HIF-2 Alpha) in Oral Squamous Cell Carcinoma: An Immunohistochemical Study
por: Mahapatra, Niva, et al.
Publicado: (2023)

Metabolic alterations accompanying oncogene-induced senescence
por: Aird, Katherine M, et al.
Publicado: (2014)

Role of ADAM17 in the non-cell autonomous effects of oncogene-induced senescence
por: Morancho, Beatriz, et al.
Publicado: (2015)

Characterization of the p53 Response to Oncogene-Induced Senescence
por: Ruiz, Lidia, et al.
Publicado: (2008)

Role of hypoxia-inducible factor 1alpha in the integrity of articular cartilage in murine knee joints
por: Gelse, Kolja, et al.
Publicado: (2008)

Prognostic role of hypoxia-inducible factor-1 alpha expression in osteosarcoma: a meta-analysis
por: Ren, Hai-Yong, et al.
Publicado: (2016)

NQO1 Stabilizes p53 in Response to Oncogene-Induced Senescence
por: Liu, Kaiyu, et al.
Publicado: (2015)

Vorinostat suppresses hypoxia signaling by modulating nuclear translocation of hypoxia inducible factor 1 alpha
por: Zhang, Chao, et al.
Publicado: (2017)

The effect of hypoxia-inducible factor 1-alpha on hypoxia-induced apoptosis in primary neonatal rat ventricular myocytes
por: Zhou, Yan-Fang, et al.
Publicado: (2010)

Viral subversion of autophagy impairs oncogene-induced senescence
por: Leidal, Andrew M., et al.
Publicado: (2012)

Hypoxia inducible factor-1 alpha as a therapeutic target in multiple myeloma
por: Borsi, Enrica, et al.
Publicado: (2014)

Hypoxic regulation of hypoxia inducible factor 1 alpha via antisense transcription
por: Downes, Nicholas, et al.
Publicado: (2023)

Krüppel-Like Factor 6 Is Required for Oxidative and Oncogene-Induced Cellular Senescence
por: Sabatino, Maria Eugenia, et al.
Publicado: (2019)

Limited Role of Murine ATM in Oncogene-Induced Senescence and p53-Dependent Tumor Suppression
por: Efeyan, Alejo, et al.
Publicado: (2009)

Estrogen receptor alpha inhibits senescence-like phenotype and facilitates transformation induced by oncogenic ras in human mammary epithelial cells
por: Liu, Zhao, et al.
Publicado: (2016)

Alcohol-Induced Glycolytic Shift in Alveolar Macrophages Is Mediated by Hypoxia-Inducible Factor-1 Alpha
por: Morris, Niya L., et al.
Publicado: (2022)

Glucose metabolism and hexosamine pathway regulate oncogene-induced senescence
por: Gitenay, D, et al.
Publicado: (2014)

Glucose metabolism and hexosamine pathway regulate oncogene-induced senescence
por: Gitenay, D, et al.
Publicado: (2014)

Perturbation of nucleotide metabolism - the driving force of oncogene-induced senescence
por: Darzynkiewicz, Zbigniew
Publicado: (2013)

Hypoxia-inducible factor-1 alpha as a therapeutic target for primary effusion lymphoma
por: Shrestha, Prabha, et al.
Publicado: (2017)

Non-Canonical Mechanisms Regulating Hypoxia-Inducible Factor 1 Alpha in Cancer
por: Iommarini, Luisa, et al.
Publicado: (2017)

Anti-Cancer Activity of Phytochemicals Targeting Hypoxia-Inducible Factor-1 Alpha
por: Yun, Ba Da, et al.
Publicado: (2021)

Hypoxia‐inducible factor 1‐alpha acts as a bridge factor for crosstalk between ERK1/2 and caspases in hypoxia‐induced apoptosis of cementoblasts
por: Yong, Jiawen, et al.
Publicado: (2021)

Hypoxia-Inducible Factor-1alpha and MAPK Co-Regulate Activation of Hepatic Stellate Cells upon Hypoxia Stimulation
por: Wang, Yueqin, et al.
Publicado: (2013)

Hypoxia Inducible Factor 1-Alpha (HIF-1 Alpha) Is Induced during Reperfusion after Renal Ischemia and Is Critical for Proximal Tubule Cell Survival
por: Conde, Elisa, et al.
Publicado: (2012)

Hypoxia-Inducible Factor-1α: The Master Regulator of Endothelial Cell Senescence in Vascular Aging
por: Alique, Matilde, et al.
Publicado: (2020)

Ras oncogene and Hypoxia-inducible factor-1 alpha (hif-1α) expression in the Amazon fish Colossoma macropomum (Cuvier, 1818) exposed to benzo[a]pyrene.
por: da Silva, Grazyelle Sebrenski, et al.
Publicado: (2017)

Puerarin decreases hypoxia inducible factor-1 alpha in the hippocampus of vascular dementia rats☆
por: Wu, Haiqin, et al.
Publicado: (2012)

Prognostic significance of Hypoxia-Inducible Factor 1 alpha(HIF-1alpha) expression in serous ovarian cancer: an immunohistochemical study
por: Daponte, Alexandros, et al.
Publicado: (2008)

Hypoxia Inducible Factor-1alpha (HIF-1A) plays different roles in Gallbladder Cancer and Normal Gallbladder Tissues
por: Wu, Youliang, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_b13kjdoobvohb2lmgv497p364t