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Evolutionary Origin of GnIH and NPFF in Chordates: Insights from Novel Amphioxus RFamide Peptides

Gonadotropin-inhibitory hormone (GnIH) is a newly identified hypothalamic neuropeptide that inhibits pituitary hormone secretion in vertebrates. GnIH has an LPXRFamide (X = L or Q) motif at the C-terminal in representative species of gnathostomes. On the other hand, neuropeptide FF (NPFF), a neurope...

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Detalles Bibliográficos
Autores principales: Osugi, Tomohiro, Okamura, Tomoki, Son, You Lee, Ohkubo, Makoto, Ubuka, Takayoshi, Henmi, Yasuhisa, Tsutsui, Kazuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077772/
https://www.ncbi.nlm.nih.gov/pubmed/24983238
http://dx.doi.org/10.1371/journal.pone.0100962