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RNA-Seq Analysis to Identify Novel Roles of Scleraxis during Embryonic Mouse Heart Valve Remodeling

Heart valve disease affects up to 30% of the population and has been shown to have origins during embryonic development. Valvulogenesis begins with formation of endocardial cushions in the atrioventricular canal and outflow tract regions. Subsequently, endocardial cushions remodel, elongate and prog...

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Detalles Bibliográficos
Autores principales: Barnette, Damien N., VandeKopple, Matthew, Wu, Yonggan, Willoughby, David A., Lincoln, Joy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077804/
https://www.ncbi.nlm.nih.gov/pubmed/24983472
http://dx.doi.org/10.1371/journal.pone.0101425