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RPM-1 is localized to distinct subcellular compartments and regulates axon length in GABAergic motor neurons

BACKGROUND: The PAM/Highwire/RPM-1 (PHR) proteins are conserved signaling proteins that regulate axon length and synapse formation during development. Loss of function in Caenorhabditis elegans rpm-1 results in axon termination and synapse formation defects in the mechanosensory neurons. An explanat...

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Detalles Bibliográficos
Autores principales: Opperman, Karla J, Grill, Brock
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077836/
https://www.ncbi.nlm.nih.gov/pubmed/24885325
http://dx.doi.org/10.1186/1749-8104-9-10