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Clinicopathological and biological significance of aberrant activation of glycogen synthase kinase-3 in ovarian cancer

BACKGROUND: Glycogen synthase kinase-3 (GSK-3) plays an important role in human cancer. The aim of this study is to evaluate the clinicopathological significance of expression of GSK-3α/β and pGSK-3α/β(Tyr279/216) in patients with epithelial ovarian cancer and to investigate whether GSK-3 inhibition...

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Detalles Bibliográficos
Autores principales: Fu, Yunfeng, Wang, Xinyu, Cheng, Xiaodong, Ye, Feng, Xie, Xing, Lu, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077858/
https://www.ncbi.nlm.nih.gov/pubmed/25028561
http://dx.doi.org/10.2147/OTT.S62158