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Dual therapeutic benefit of electroporation-mediated DNA vaccination in vivo: Enhanced gene transfer and adjuvant activity

DNA vaccination consists of administering an antigen-coding nucleotide sequence. In order to improve the efficacy of DNA vaccines, electroporation is one of the most commonly used methods to enhance DNA uptake. Here, we discuss additional immunological effects of electroporation that are key aspects...

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Detalles Bibliográficos
Autores principales: Calvet, Christophe Y, André, Franck M, Mir, Lluis M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077865/
https://www.ncbi.nlm.nih.gov/pubmed/25050220
http://dx.doi.org/10.4161/onci.28540