Dual therapeutic benefit of electroporation-mediated DNA vaccination in vivo: Enhanced gene transfer and adjuvant activity

DNA vaccination consists of administering an antigen-coding nucleotide sequence. In order to improve the efficacy of DNA vaccines, electroporation is one of the most commonly used methods to enhance DNA uptake. Here, we discuss additional immunological effects of electroporation that are key aspects...

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Detalles Bibliográficos
Autores principales: Calvet, Christophe Y, André, Franck M, Mir, Lluis M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Point of View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077865/
https://www.ncbi.nlm.nih.gov/pubmed/25050220
http://dx.doi.org/10.4161/onci.28540
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author Calvet, Christophe Y
André, Franck M
Mir, Lluis M
author_facet Calvet, Christophe Y
André, Franck M
Mir, Lluis M
author_sort Calvet, Christophe Y
collection PubMed
description DNA vaccination consists of administering an antigen-coding nucleotide sequence. In order to improve the efficacy of DNA vaccines, electroporation is one of the most commonly used methods to enhance DNA uptake. Here, we discuss additional immunological effects of electroporation that are key aspects for inducing immunity in response to DNA vaccines.
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spelling pubmed-40778652014-07-21 Dual therapeutic benefit of electroporation-mediated DNA vaccination in vivo: Enhanced gene transfer and adjuvant activity Calvet, Christophe Y André, Franck M Mir, Lluis M Oncoimmunology Point of View DNA vaccination consists of administering an antigen-coding nucleotide sequence. In order to improve the efficacy of DNA vaccines, electroporation is one of the most commonly used methods to enhance DNA uptake. Here, we discuss additional immunological effects of electroporation that are key aspects for inducing immunity in response to DNA vaccines. Landes Bioscience 2014-04-29 /pmc/articles/PMC4077865/ /pubmed/25050220 http://dx.doi.org/10.4161/onci.28540 Text en Copyright © 2014 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Point of View
Calvet, Christophe Y
André, Franck M
Mir, Lluis M
Dual therapeutic benefit of electroporation-mediated DNA vaccination in vivo: Enhanced gene transfer and adjuvant activity
title Dual therapeutic benefit of electroporation-mediated DNA vaccination in vivo: Enhanced gene transfer and adjuvant activity
title_full Dual therapeutic benefit of electroporation-mediated DNA vaccination in vivo: Enhanced gene transfer and adjuvant activity
title_fullStr Dual therapeutic benefit of electroporation-mediated DNA vaccination in vivo: Enhanced gene transfer and adjuvant activity
title_full_unstemmed Dual therapeutic benefit of electroporation-mediated DNA vaccination in vivo: Enhanced gene transfer and adjuvant activity
title_short Dual therapeutic benefit of electroporation-mediated DNA vaccination in vivo: Enhanced gene transfer and adjuvant activity
title_sort dual therapeutic benefit of electroporation-mediated dna vaccination in vivo: enhanced gene transfer and adjuvant activity
topic Point of View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077865/
https://www.ncbi.nlm.nih.gov/pubmed/25050220
http://dx.doi.org/10.4161/onci.28540
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