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Atg17/FIP200 localizes to perilysosomal Ref(2)P aggregates and promotes autophagy by activation of Atg1 in Drosophila

Phagophore-derived autophagosomes deliver cytoplasmic material to lysosomes for degradation and reuse. Autophagy mediated by the incompletely characterized actions of Atg proteins is involved in numerous physiological and pathological settings including stress resistance, immunity, aging, cancer, an...

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Detalles Bibliográficos
Autores principales: Nagy, Péter, Kárpáti, Manuéla, Varga, Ágnes, Pircs, Karolina, Venkei, Zsolt, Takáts, Szabolcs, Varga, Kata, Érdi, Balázs, Hegedűs, Krisztina, Juhász, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077884/
https://www.ncbi.nlm.nih.gov/pubmed/24419107
http://dx.doi.org/10.4161/auto.27442