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Loss of 5-hydroxymethylcytosine correlates with increasing morphologic dysplasia in melanocytic tumors

DNA methylation is the most well studied epigenetic modification in cancer biology. 5-hydroxymethylcytosine is an epigenetic mark that can be converted from 5-methylcytosine by the ten-eleven translocation gene family. We recently reported the loss of 5-hydroxymethylcytosine in melanoma compared to...

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Detalles Bibliográficos
Autores principales: Larson, Allison R., Dresser, Karen, Zhan, Qian, Lezcano, Cecilia, Woda, Bruce A., Yosufi, Benafsha, Thompson, John F., Scolyer, Richard A., Mihm, Martin C., Shi, Yujiang G., Murphy, George F., Lian, Christine Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077910/
https://www.ncbi.nlm.nih.gov/pubmed/24390216
http://dx.doi.org/10.1038/modpathol.2013.224