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Mitochondrial reactive oxygen species accelerate the expression of heme carrier protein 1 and enhance photodynamic cancer therapy effect

Photodynamic therapy using hematoporphyrin and its derivatives is clinically useful for cancer treatments. It has been reported that cancer cells incorporate hematoporphyrin and its derivatives via heme carrier protein 1, which is a proton-coupled folate transporter. However, the mechanism of this p...

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Detalles Bibliográficos
Autores principales: Ito, Hiromu, Matsui, Hirofumi, Tamura, Masato, Majima, Hideyuki J., Indo, Hiroko P., Hyodo, Ichinosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078070/
https://www.ncbi.nlm.nih.gov/pubmed/25120282
http://dx.doi.org/10.3164/jcbn.14-27