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Methylation-capture and Next-Generation Sequencing of free circulating DNA from human plasma

BACKGROUND: Free circulating DNA (fcDNA) has many potential clinical applications, due to the non-invasive way in which it is collected. However, because of the low concentration of fcDNA in blood, genome-wide analysis carries many technical challenges that must be overcome before fcDNA studies can...

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Detalles Bibliográficos
Autores principales: Warton, Kristina, Lin, Vita, Navin, Tina, Armstrong, Nicola J, Kaplan, Warren, Ying, Kevin, Gloss, Brian, Mangs, Helena, Nair, Shalima S, Hacker, Neville F, Sutherland, Robert L, Clark, Susan J, Samimi, Goli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078241/
https://www.ncbi.nlm.nih.gov/pubmed/24929644
http://dx.doi.org/10.1186/1471-2164-15-476