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Emerging Concepts about NAIP/NLRC4 Inflammasomes

Neuronal apoptosis inhibitory protein (NAIP)/NOD-like receptor (NLR) containing a caspase activating and recruitment domain (CARD) 4 (NLRC4) inflammasome complexes are activated in response to proteins from virulent bacteria that reach the cell cytosol. Specific NAIP proteins bind to the agonists an...

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Detalles Bibliográficos
Autores principales: Lage, Silvia Lucena, Longo, Carla, Branco, Laura Migliari, da Costa, Thaís Boccia, Buzzo, Carina de Lima, Bortoluci, Karina Ramalho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078251/
https://www.ncbi.nlm.nih.gov/pubmed/25071770
http://dx.doi.org/10.3389/fimmu.2014.00309