β-amyloid deposition is shifted to the vasculature and memory impairment is exacerbated when hyperhomocysteinemia is induced in APP/PS1 transgenic mice

INTRODUCTION: Vascular dementia is the second most common cause of dementia after Alzheimer’s disease (AD). In addition, it is estimated that almost half of all AD patients have significant cerebrovascular disease comorbid with their AD pathology. We hypothesized that cerebrovascular disease signifi...

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Detalles Bibliográficos
Autores principales: Sudduth, Tiffany L, Weekman, Erica M, Brothers, Holly M, Braun, Kaitlyn, Wilcock, Donna M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078260/
https://www.ncbi.nlm.nih.gov/pubmed/24991237
http://dx.doi.org/10.1186/alzrt262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078260/
https://www.ncbi.nlm.nih.gov/pubmed/24991237
http://dx.doi.org/10.1186/alzrt262

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