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β-amyloid deposition is shifted to the vasculature and memory impairment is exacerbated when hyperhomocysteinemia is induced in APP/PS1 transgenic mice
INTRODUCTION: Vascular dementia is the second most common cause of dementia after Alzheimer’s disease (AD). In addition, it is estimated that almost half of all AD patients have significant cerebrovascular disease comorbid with their AD pathology. We hypothesized that cerebrovascular disease signifi...
Autores principales: | Sudduth, Tiffany L, Weekman, Erica M, Brothers, Holly M, Braun, Kaitlyn, Wilcock, Donna M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078260/ https://www.ncbi.nlm.nih.gov/pubmed/24991237 http://dx.doi.org/10.1186/alzrt262 |
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