Nafamostat mesilate attenuates neuronal damage in a rat model of transient focal cerebral ischemia through thrombin inhibition

Evidence suggests that thrombin, a blood coagulation serine protease, mediates neuronal injury in experimental cerebral ischemia. Here, we test the hypothesis that nafamostat mesilate, a serine protease inhibitor, may ameliorate ischemia-induced neuronal damage through thrombin inhibition after isch...

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Detalles Bibliográficos
Autores principales: Chen, Tao, Wang, Jing, Li, Chenhui, Zhang, Weining, Zhang, Luyong, An, Lufan, Pang, Tao, Shi, Xinzhong, Liao, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078306/
https://www.ncbi.nlm.nih.gov/pubmed/24985053
http://dx.doi.org/10.1038/srep05531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078306/
https://www.ncbi.nlm.nih.gov/pubmed/24985053
http://dx.doi.org/10.1038/srep05531

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