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An attempt to stabilize tanshinone IIA solid dispersion by the use of ternary systems with nano-CaCO(3) and poloxamer 188

BACKGROUND: Tanshinone IIA (TSIIA) on solid dispersions (SDs) has thermodynamical instability of amorphous drug. Ternary solid dispersions (tSDs) can extend the stability of the amorphous form of drug. Poloxamer 188 was used as a SD carrier. Nano-CaCO(3) played an important role in adsorption of bio...

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Detalles Bibliográficos
Autores principales: Yan, Hong-mei, Zhang, Zhen-hai, Jiang, Yan-rong, Ding, Dong-mei, Sun, E., Jia, Xiao-bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078353/
https://www.ncbi.nlm.nih.gov/pubmed/24991109
http://dx.doi.org/10.4103/0973-1296.133286