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An attempt to stabilize tanshinone IIA solid dispersion by the use of ternary systems with nano-CaCO(3) and poloxamer 188
BACKGROUND: Tanshinone IIA (TSIIA) on solid dispersions (SDs) has thermodynamical instability of amorphous drug. Ternary solid dispersions (tSDs) can extend the stability of the amorphous form of drug. Poloxamer 188 was used as a SD carrier. Nano-CaCO(3) played an important role in adsorption of bio...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Medknow Publications & Media Pvt Ltd
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078353/ https://www.ncbi.nlm.nih.gov/pubmed/24991109 http://dx.doi.org/10.4103/0973-1296.133286 |