Cargando…

Insight into model mechanisms through automatic parameter fitting: a new methodological framework for model development

BACKGROUND: Striking a balance between the degree of model complexity and parameter identifiability, while still producing biologically feasible simulations using modelling is a major challenge in computational biology. While these two elements of model development are closely coupled, parameter fit...

Descripción completa

Detalles Bibliográficos
Autores principales: Tøndel, Kristin, Niederer, Steven A, Land, Sander, Smith, Nicolas P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078362/
https://www.ncbi.nlm.nih.gov/pubmed/24886522
http://dx.doi.org/10.1186/1752-0509-8-59