Cargando…

A comparison of three (67/68)Ga-labelled exendin-4 derivatives for β-cell imaging on the GLP-1 receptor: the influence of the conjugation site of NODAGA as chelator

BACKGROUND: Various diseases derive from pathologically altered β-cells. Their function can be increased, leading to hyperinsulinism, or decreased, resulting in diabetes. Non-invasive imaging of the β-cell-specific glucagon-like peptide receptor-1 (GLP-1R) would allow the assessment of both β-cell m...

Descripción completa

Detalles Bibliográficos
Autores principales: Jodal, Andreas, Lankat-Buttgereit, Brigitte, Brom, Maarten, Schibli, Roger, Béhé, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078388/
https://www.ncbi.nlm.nih.gov/pubmed/25006548
http://dx.doi.org/10.1186/s13550-014-0031-9