NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases

Transformation by tyrosine kinase oncogenes in myeloid malignancies, including BCR-ABL in chronic myeloid leukemia, FLT3ITD in acute myeloid leukemia (AML) or JAK2V617F in myeloproliferative neoplasms (MPN), is associated with increased growth and cytoskeletal abnormalities. Using targeted approache...

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Detalles Bibliográficos
Autores principales: Reddy, Mamatha M., Fernandes, Margret S., Salgia, Ravi, Levine, Ross L., Griffin, James D., Sattler, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078661/
https://www.ncbi.nlm.nih.gov/pubmed/21072051
http://dx.doi.org/10.1038/leu.2010.263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078661/
https://www.ncbi.nlm.nih.gov/pubmed/21072051
http://dx.doi.org/10.1038/leu.2010.263

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