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NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases
Transformation by tyrosine kinase oncogenes in myeloid malignancies, including BCR-ABL in chronic myeloid leukemia, FLT3ITD in acute myeloid leukemia (AML) or JAK2V617F in myeloproliferative neoplasms (MPN), is associated with increased growth and cytoskeletal abnormalities. Using targeted approache...
Autores principales: | Reddy, Mamatha M., Fernandes, Margret S., Salgia, Ravi, Levine, Ross L., Griffin, James D., Sattler, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078661/ https://www.ncbi.nlm.nih.gov/pubmed/21072051 http://dx.doi.org/10.1038/leu.2010.263 |
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