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DNA Ministrings: Highly Safe and Effective Gene Delivery Vectors
Conventional plasmid DNA vectors play a significant role in gene therapy, but they also have considerable limitations: they can elicit adverse immune responses because of bacterial sequences they contain for maintenance and amplification in prokaryotes, their bioavailability is compromised because o...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078758/ https://www.ncbi.nlm.nih.gov/pubmed/24892724 http://dx.doi.org/10.1038/mtna.2014.16 |