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Aptamer-facilitated Protection of Oncolytic Virus from Neutralizing Antibodies

Oncolytic viruses promise to significantly improve current cancer treatments through their tumor-selective replication and multimodal attack against cancer cells. However, one of the biggest setbacks for oncolytic virus therapy is the intravenous delivery of the virus, as it can be cleared from the...

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Detalles Bibliográficos
Autores principales: Muharemagic, Darija, Zamay, Anna, Ghobadloo, Shahrokh M, Evgin, Laura, Savitskaya, Anna, Bell, John C, Berezovski, Maxim V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078759/
https://www.ncbi.nlm.nih.gov/pubmed/24892725
http://dx.doi.org/10.1038/mtna.2014.19