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Aptamer-facilitated Protection of Oncolytic Virus from Neutralizing Antibodies
Oncolytic viruses promise to significantly improve current cancer treatments through their tumor-selective replication and multimodal attack against cancer cells. However, one of the biggest setbacks for oncolytic virus therapy is the intravenous delivery of the virus, as it can be cleared from the...
Autores principales: | Muharemagic, Darija, Zamay, Anna, Ghobadloo, Shahrokh M, Evgin, Laura, Savitskaya, Anna, Bell, John C, Berezovski, Maxim V |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078759/ https://www.ncbi.nlm.nih.gov/pubmed/24892725 http://dx.doi.org/10.1038/mtna.2014.19 |
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