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Development and Bioorthogonal Activation of Palladium-Labile Prodrugs of Gemcitabine

[Image: see text] Bioorthogonal chemistry has become one of the main driving forces in current chemical biology, inspiring the search for novel biocompatible chemospecific reactions for the past decade. Alongside the well-established labeling strategies that originated the bioorthogonal paradigm, we...

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Detalles Bibliográficos
Autores principales: Weiss, Jason T., Dawson, John C., Fraser, Craig, Rybski, Witold, Torres-Sánchez, Carmen, Bradley, Mark, Patton, E. Elizabeth, Carragher, Neil O., Unciti-Broceta, Asier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078945/
https://www.ncbi.nlm.nih.gov/pubmed/24867590
http://dx.doi.org/10.1021/jm500531z