The copper chelator ATN-224 induces caspase-independent cell death in diffuse large B cell lymphoma

Bcl-2 and other anti-apoptotic proteins are associated with defective caspase-dependent apoptotic pathways, resulting in chemoresistance. We have previously shown that ATN-224, a copper chelator drug, induces cell death in murine thymic lymphoma cells transfected with Bcl-2. In the current study, we...

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Detalles Bibliográficos
Autores principales: LEE, KRISTY, HART, MATTHEW R., BRIEHL, MARGARET M., MAZAR, ANDREW P., TOME, MARGARET E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079159/
https://www.ncbi.nlm.nih.gov/pubmed/24788952
http://dx.doi.org/10.3892/ijo.2014.2396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079159/
https://www.ncbi.nlm.nih.gov/pubmed/24788952
http://dx.doi.org/10.3892/ijo.2014.2396

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