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Selecting biologically informative genes in co-expression networks with a centrality score

BACKGROUND: Measures of node centrality in biological networks are useful to detect genes with critical functional roles. In gene co-expression networks, highly connected genes (i.e., candidate hubs) have been associated with key disease-related pathways. Although different approaches to estimating...

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Detalles Bibliográficos
Autor principal: Azuaje, Francisco J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079186/
https://www.ncbi.nlm.nih.gov/pubmed/24947308
http://dx.doi.org/10.1186/1745-6150-9-12