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Selecting biologically informative genes in co-expression networks with a centrality score
BACKGROUND: Measures of node centrality in biological networks are useful to detect genes with critical functional roles. In gene co-expression networks, highly connected genes (i.e., candidate hubs) have been associated with key disease-related pathways. Although different approaches to estimating...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079186/ https://www.ncbi.nlm.nih.gov/pubmed/24947308 http://dx.doi.org/10.1186/1745-6150-9-12 |