Weak Negative and Positive Selection and the Drift Load at Splice Sites

Splice sites (SSs) are short sequences that are crucial for proper mRNA splicing in eukaryotic cells, and therefore can be expected to be shaped by strong selection. Nevertheless, in mammals and in other intron-rich organisms, many of the SSs often involve nonconsensus (Nc), rather than consensus (C...

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Detalles Bibliográficos
Autores principales: Denisov, Stepan V., Bazykin, Georgii A., Sutormin, Roman, Favorov, Alexander V., Mironov, Andrey A., Gelfand, Mikhail S., Kondrashov, Alexey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079205/
https://www.ncbi.nlm.nih.gov/pubmed/24966225
http://dx.doi.org/10.1093/gbe/evu100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079205/
https://www.ncbi.nlm.nih.gov/pubmed/24966225
http://dx.doi.org/10.1093/gbe/evu100

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