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Biomechanics and Thermodynamics of Nanoparticle Interactions with Plasma and Endosomal Membrane Lipids in Cellular Uptake and Endosomal Escape

[Image: see text] To be effective for cytoplasmic delivery of therapeutics, nanoparticles (NPs) taken up via endocytic pathways must efficiently transport across the cell membrane and subsequently escape from the secondary endosomes. We hypothesized that the biomechanical and thermodynamic interacti...

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Detalles Bibliográficos
Autores principales: Peetla, Chiranjeevi, Jin, Shihua, Weimer, Jonathan, Elegbede, Adekunle, Labhasetwar, Vinod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079324/
https://www.ncbi.nlm.nih.gov/pubmed/24911361
http://dx.doi.org/10.1021/la5015219