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Biomechanics and Thermodynamics of Nanoparticle Interactions with Plasma and Endosomal Membrane Lipids in Cellular Uptake and Endosomal Escape
[Image: see text] To be effective for cytoplasmic delivery of therapeutics, nanoparticles (NPs) taken up via endocytic pathways must efficiently transport across the cell membrane and subsequently escape from the secondary endosomes. We hypothesized that the biomechanical and thermodynamic interacti...
Autores principales: | Peetla, Chiranjeevi, Jin, Shihua, Weimer, Jonathan, Elegbede, Adekunle, Labhasetwar, Vinod |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079324/ https://www.ncbi.nlm.nih.gov/pubmed/24911361 http://dx.doi.org/10.1021/la5015219 |
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