Saccharin Derivatives as Inhibitors of Interferon-Mediated Inflammation

[Image: see text] A series of novel, saccharin-based antagonists have been identified for the interferon signaling pathway. Through in vitro high-throughput screening with the Colorado Center for Drug Discovery (C2D2) Pilot Library, we identified hit compound 1, which was the basis for extensive str...

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Detalles Bibliográficos
Autores principales: Csakai, Adam, Smith, Christina, Davis, Emily, Martinko, Alexander, Coulup, Sara, Yin, Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079330/
https://www.ncbi.nlm.nih.gov/pubmed/24897296
http://dx.doi.org/10.1021/jm500409k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079330/
https://www.ncbi.nlm.nih.gov/pubmed/24897296
http://dx.doi.org/10.1021/jm500409k

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