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Saccharin Derivatives as Inhibitors of Interferon-Mediated Inflammation
[Image: see text] A series of novel, saccharin-based antagonists have been identified for the interferon signaling pathway. Through in vitro high-throughput screening with the Colorado Center for Drug Discovery (C2D2) Pilot Library, we identified hit compound 1, which was the basis for extensive str...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079330/ https://www.ncbi.nlm.nih.gov/pubmed/24897296 http://dx.doi.org/10.1021/jm500409k |